Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer

Cochrane review: Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer

Evidence news! A Cochrane review has been published investigating uncut Roux‐en‐Y reconstruction after distal gastrectomy for gastric cancer.

Objectives: To assess the benefits and harms of uncut Roux‐en‐Y reconstruction after distal gastrectomy in patients with gastric cancer.

Main results: Eight trials with 1167 participants were included.

Uncut Roux‐en‐Y reconstruction versus Billroth II reconstruction

  • Uncut Roux‐en‐Y reconstruction may have little to no effect on major postoperative complications, anastomotic leakage, and remnant gastritis but the evidence is very uncertain.
  • Uncut Roux‐en‐Y reconstruction may reduce bile reflux slightly.
  • Uncut Roux‐en‐Y reconstruction versus Roux‐en‐Y reconstruction
  • Uncut Roux‐en‐Y reconstruction may have little to no effect on major postoperative complications, anastomotic leakage, remnant gastritis, and esophagitis but the evidence is very uncertain.
  • Uncut Roux‐en‐Y reconstruction may increase bile reflux but the evidence is very uncertain.

Authors' conclusion: Most critical outcomes may be comparable between the uncut Roux‐en‐Y reconstruction and other methods, but authors are very uncertain about most of these results. Nevertheless, it indicates that uncut Roux‐en‐Y reconstruction may reduce the incidence of bile reflux compared with Billroth‐II reconstruction, albeit with low certainty. In contrast, compared with Roux‐en‐Y reconstruction, uncut Roux‐en‐Y may increase bile reflux incidence, based on very low‐certainty evidence.

Access publication here: https://doi.org/10.1002/14651858.CD015014.pub2

Visual abstract for Cochrane review: Uncut Roux-en-Y reconstruction after distal gastrectomy for gastric cancer